Autodesk Foundation & Microdesk collaborated with the nonprofit Build Health International (BHI) to leverage early computational design workflows to identify, optimize, and implement passive design strategies that have the most significant impact on the building performance. We utilized site and climate data in concert with passive strategies to inform the design of the façade to promote ideal ventilation to address infection control, operational cost, and occupant comfort. These considerations are a crucial aspect of optimizing and utilizing natural ventilation strategies. BHI works in communities where sustainability is a necessity and not for certification or because "it is a neat thing". These workflows saved the design team countless hours by enabling them time to study thousands of iterations at a moment's notice making our design process nimble and efficient, allowing the design team to focus resources where they will significantly impact the project.